It's late in the 21st century, and bioengineering is now so common that people can modify their minds in any way they wish. The era has been shaped by information systems so vast that security in any form is easily breached. Now you can be whatever you want and do whatever you want—on Earth, anyway.
One night, thirty-three years ago, the stars went out. 'The Bubble'—a perfect sphere centered on the sun—appeared in the sky, isolating the solar system from the rest of the universe. For thirty-three years, humanity has lived with the religious cults and terrorism which spawned in the wake of the darkness. We are now alone. Humanity has been cut off. Quarantined.